Abstract
Atypical organisms (Chlamydia pneumoniae, Mycoplasma pneumoniae) have been recently linked to asthma in various ways: an infection with these organisms may precede asthma onset, exacerbate asthma, or make asthma control more difficult. Their ability to elicit a TH2 response and promote airway inflammation may be the common pathway in the development of an atopic inflammatory response. This article presents a summary of the evidence that infection with Chlamydia pneumoniae or Mycoplasma pneumoniae may play a significance role in asthma.
MeSH terms
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Asthma / immunology
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Asthma / microbiology*
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Child
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Child, Preschool
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Chlamydia Infections / complications*
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Chlamydia Infections / diagnosis
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Chlamydophila pneumoniae / isolation & purification*
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Female
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Humans
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Male
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Middle Aged
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Mycoplasma pneumoniae / isolation & purification*
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Opportunistic Infections / complications*
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Opportunistic Infections / diagnosis
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Pneumonia, Mycoplasma / complications*
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Pneumonia, Mycoplasma / diagnosis
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Prognosis
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Randomized Controlled Trials as Topic
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Risk Assessment