Parameter estimates (95% CIs) and likelihood ratio test (LRT) p values for the effect of diagnosis by NBS on weight-for-age SD-score trajectories, BM-for-age SD-score trajectories, %predicted FEV1 and cPA after adjustment for sex, genotype, year of birth, ethnicity, diagnosis by MI and pancreatic insufficiency. All numbers were rounded to two digits
| Weight | BMI | %FEV1 | cPA | |
| Model with NBS main effect only | ||||
| NBS effect estimate | 0.11 (0.03, 0.19) | 0.02 (−0.05, 0.09) | 1.56 (0.1, 3.02) | 1.31 (1.07, 1.62) |
| LRT p value | <0.01 | 0.54 | 0.04 | <0.01 |
| Model with NBS main effect and interaction with age | ||||
| NBS effect estimate | 0.16 (0.07, 0.26) | 0.05 (−0.05, 0.14) | 0.87 (−0.88, 2.62) | NA |
| NBS:age interaction effect estimate | −0.02 (−0.03, −0.00) | −0.01 (−0.02, 0.01) | 0.24 (−0.1, 0.58) | NA |
| LRT p value* | 0.02 | 0.42 | 0.16 | NA |
*Compared with model with NBS main effect only.
BMI, body mass index; cPA, chronic Pseudomonas aeruginosa; FEV1, forced expiratory volume in one second; NBS, newborn bloodspot screening.