Description of the children hospitalised for severe bronchiolitis according to the profiles (A to D) identified by LCA, for the clinical characteristics introduced in the LCA model, MARC-30 USA, n=2207
| All | Profiles | ||||
|---|---|---|---|---|---|
| A (12%) | B (36%) | C (34%) | D (17%) | ||
| History of wheezing | 23 | 48 | 21 | 19 | 12 |
| History of eczema | 14 | 32 | 15 | 10 | 7 |
| Wheeze at ED presentation | 64 | 90 | 82 | 63 | 11 |
| Cough at ED presentation | 86 | 92 | 93 | 83 | 74 |
| Retractions at ED presentation | |||||
| None | 24 | 18 | 19 | 11 | 61 |
| Mild | 45 | 47 | 56 | 39 | 34 |
| Moderate to severe | 31 | 35 | 24 | 50 | 5 |
| Hospital length of stay (days) | |||||
| <3 | 56 | 82 | 75 | 16 | 77 |
| 3–6 | 33 | 15 | 24 | 58 | 18 |
| ≥7 | 11 | 3 | <1 | 27 | 5 |
| Retractions during hospital stay | |||||
| None | 34 | 44 | 47 | 2 | 69 |
| Mild | 46 | 47 | 53 | 46 | 30 |
| Moderate to severe | 20 | 9 | <1 | 52 | <1 |
| Viral aetiology | |||||
| RSV | 72 | 18 | 89 | 82 | 63 |
| Rhinovirus | 26 | 66 | 12 | 24 | 23 |
Results are expressed as % (observed proportion in the study population (‘All’), and probability of individuals presenting the characteristics within profiles A to D).
Profile A: history of wheezing/eczema, wheezing at ED presentation, more often rhinovirus. Profile B: wheezing at ED presentation, more often RSV only. Profile C: most severe. Profile D: non-wheezing at ED presentation, least severe.
ED, emergency department; LCA, latent class analysis; RSV, respiratory syncytial virus.