Degree of airflow obstruction in groups with persistent asthma by adequacy of treatment
| Persistent severity groups | N (%)* | FEV1/FVC post-BD† | Difference in mean FEV1/FVC post-BD‡ | ||
| Mean (95% CI) | Difference (95% CI) | p Value | |||
| Inadequate preventer users (n = 140) | Mild | 50 (35.7%) | 76.83 (74.32 to 79.34) | 0.00 | |
| Moderate | 58 (41.4%) | 74.15 (71.80 to 76.51) | −2.68 (−6.14 to 0.78) | 0.128 | |
| Severe | 32 (22.9%) | 72.78 (65.95 to 79.62) | −4.80 (−8.86 to −0.74) | 0.021 | |
| Adequate preventer users (n = 40) | Mild | 22 (55.0%) | 75.05 (70.82 to 79.28) | 0.00 | |
| Moderate | 9 (22.5%) | 73.31 (66.54 to 80.09) | −1.74 (−9.56 to 6.08) | 0.653 | |
| Severe | 9 (22.5%) | 77.66 (70.29 to 85.03) | 2.61 (−6.13 to 11.34) | 0.547 | |
*Limited to participants with lung function data.
†Adjusted for smoking, gender, age, height and weight.
‡Calculated using multiple linear regression model for the two adequacy groups separately.
BD, bronchodilator; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity.