Clinical and functional characteristics of study patients
| Intervention group(N = 298) | Non-intervention group (N = 298) | p value | |
|---|---|---|---|
| FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; TB, tuberculosis. | |||
| Values are expressed as median (interquartile range) or n (%). | |||
| Two sided p values were calculated using the χ2 test for proportions and the Wilcoxon test for quantitative variables. | |||
| % Male | 96.6% | 93.3% | 0.09 |
| Follow up | 0.77 | ||
| Mean (days) | 980.0 | 977.8 | |
| Range (days) | 20–1454 | 21–1183 | |
| Total (person-years) | 800.1 | 798.0 | |
| FVC (l) | 2.0 (1.6–2.5) | 2.1 (1.7–2.6) | 0.17 |
| FVC (%) | 62 (50–73) | 63 (52–74) | 0.21 |
| FEV1 (l) | 1.1 (0.8–1.4) | 1.2 (0.8–1.5) | 0.02 |
| FEV1 (%) | 42 (32–54) | 43 (33–55) | 0.21 |
| FEV1%FVC | 53 (45–62) | 55 (45–64) | 0.21 |
| Age (years) | 69 (62–73) | 68 (61–73) | 0.23 |
| Age group | |||
| <65 years | 91 (31%) | 116 (39%) | 0.04 |
| ⩾65 years | 207 (69%) | 182 (61%) | |
| Severity of COPD | |||
| Severe (FEV1 <40%) | 132 (44%) | 114 (38%) | 0.13 |
| Non-severe (FEV1 ⩾40%) | 166 (56%) | 184 (62%) | |
| Currently smoking | 65 (22%) | 77 (26%) | 0.25 |
| Previous pneumonia | 58 (19.5%) | 52 (17.4%) | 0.53 |
| Pneumonia in previous 5 years | 33 (11%) | 28 (9.4%) | 0.50 |
| Previous TB | 22 (7.4%) | 33 (11.1%) | 0.12 |
| Neoplasia during follow up | 18 (6%) | 16 (5.3%) | 0.72 |
| Death from any cause | 57 (19.1%) | 58 (19.5%) | 0.92 |
| Death from pneumonia | 6 (2%) | 6 (2%) | 1.00 |