Muscle function and local muscle exercise parameters
| Non-hypoxaemic group(n = 9)Mean (SE) [95% CI] | Hypoxaemic group(n = 9)Mean (SE) [95% CI] | Statistical data(n = 18)Mean difference [95% CI], p value | |
|---|---|---|---|
| MCTSACT, mid thigh muscle cross sectional area; MVC, maximal voluntary contraction; HR, heart rate; Spo2, oxygen pulse saturation; Δ, change in the corresponding variable from rest to end of exercise. | |||
| *p<0.05 hypoxaemic (n = 8) v non-hypoxaemic group (n = 8). | |||
| MCTSACT (cm2) | 87 (9) [65 to 109] | 83 (7) [67 to 99] | +4 [−21 to +29]; p = 0.74 |
| MVC (kg) | 31 (4) [39 to 23] | 30 (2) [25 to 35] | +1 [−8 to +10]; p = 0.85 |
| Quadriceps endurance time (s) | 421 (72) [255 to 587] | 330 (34) [252 to 408] | +91 [−78 to +259]; p = 0.27 |
| Physical activity score | 4.5 (1.0) [2.2 to 6.8] | 3.2 (0.5) [2.2 to 4.2] | +1.2 [−1.1 to +3.6]; p = 0.29 |
| Δ HR (pulse/min) | 7 (1) [4 to 10] | 9 (1) [6 to 12] | –; –; p = 0.22 |
| Δ Spo2 (%) | 0.5 (0.4) [−0.4 to +1.4] | −2.5 (0.3) [−3.2 to +1.0]* | +3.1 [+2.1 to +4.1]; p<0.0001 |
| Δ Dyspnoea score | 2.9 (0.7) [1.3 to 4.5] | 3.5 (0.5) [2.3 to 4.7] | +0.5 [−2.4 to +1.3]; p = 0.53 |
| Δ Muscle fatigue score | 6.9 (0.6) [5.5 to 8.3] | 5.7 (0.8) [3.9 to 7.5] | +1.2 [−0.9 to +3.2]; p = 0.25 |