Protocol designs showing ventilatory patterns and inspired air conditions
| Protocol no | Target ventilation pattern | Inspired air conditions | ||||
|---|---|---|---|---|---|---|
| No of subjects | Mean FEV1 (l) | Vt (ml) | Vm (l) | Temperature(°C) | Moisture content (mg/g) | |
| Vt = tidal volume; Vm = minute ventilation; FEV1 = forced expiratory volume in 1 second. | ||||||
| 1 | 10 | 3.9 | 1500 | 7.5, 15, 22.5 | 22 (1.2) | 6 (0.3) |
| 750 | 7.5, 15, 22.5 | |||||
| 2 | 10 | 3.9 | 1500 | 15 | 7 (0.5) | 5.6 (0.2) |
| 500 | 15 | |||||
| 3 | 10 | 3.6 | 1500 | 15 | 20 (1.8) | 9 (1.1) |
| 9 (1.8) | 5 (0.5) | |||||