Association of MEF25 with birth weight status and other factors
| Difference in MEF25 (ml/s) | 95% CI of difference | p value | |
|---|---|---|---|
| *Data adjusted for those variables found to be significant in univariate analyses—that is, birth weight status, infant sex, length at test, postnatal age, and family history of asthma. | |||
| Univariate analyses | |||
| Birth weight status (baseline: appropriate birth weight for gestation) | −27.8 | −44.9 to −10.6 | 0.002 |
| Sex (baseline: female) | −19.7 | −36.8 to −2.6 | 0.02 |
| Weight at test (per kg) | 7.8 | −3.1 to 18.7 | 0.16 |
| Length at test (per cm) | 5.4 | 2.5 to 8.3 | <0.001 |
| Postnatal age (per week) | 4.8 | 0.9 to 8.7 | 0.015 |
| Maternal smoking (baseline: no maternal smoking) | −15.2 | −32.7 to 2.3 | 0.09 |
| Maternal social class (baseline: non-manual occupation) | −16.2 | −37.0 to 4.5 | 0.13 |
| Maternal height (per cm) | 0.8 | −0.5 to 2.1 | 0.22 |
| Family history of asthma (baseline: no history of asthma) | −24.7 | −43.6 to −5.8 | 0.01 |
| Multivariate analysis* | |||
| Birth weight status (baseline: appropriate birth weight for gestation) | −27.8 | −48.2 to −7.4 | 0.008 |
| Sex (baseline: female) | −22.5 | −39.7 to −5.4 | 0.01 |
| Weight at test (per kg) | −34.1 | −54.6 to −13.5 | 0.001 |
| Length at test (per cm) | 9.8 | 3.7 to 15.8 | 0.002 |
| Postnatal age (per week) | 3.4 | −2.3 to 9.2 | 0.24 |
| Maternal smoking (baseline: no maternal smoking) | −13.4 | −30.7 to 3.9 | 0.13 |
| Maternal social class (baseline: non-manual occupation) | −2.5 | −23.9 to 18.9 | 0.82 |
| Maternal height (per cm) | −0.45 | −1.8 to 0.9 | 0.50 |
| Family history of asthma (baseline: no history of asthma) | −29.6 | −47.6 to −11.6 | 0.001 |