Smoking habit and CYP2A6 genotype frequencies
| All smokers | Current smokers | Ex-smokers | Non-smokers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | Age | %D | n | Age | %D | n | Age | %D | n | Age | %D | |
| CC=lifelong cigarette consumption; duration=duration of smoking period; %D=percentage of subjects with genotype D. | ||||||||||||
| *p<0.05, **p<0.01v the rest of the subjects in each group. | ||||||||||||
| †p<0.05, ††p<0.01 v non-smokers. | ||||||||||||
| Non-smokers were younger than the subgroups of smokers except those in the 10–39 years duration group of current smokers. | ||||||||||||
| Total | 203 | 66 (9) | 30.0 | 92 | 64 (8) | 41.3 | 111 | 69 (10) | 20.7†† | 122 | 56 (3) | 36.1 |
| CC (pack years) | ||||||||||||
| 10–59 | 115 | 65 (10) | 37.4 | 52 | 63 (9) | 50.0 | 63 | 67 (11) | 27.0 | |||
| 60+ | 88 | 68 (9) | 20.5**† | 40 | 65 (8) | 30.0 | 48 | 70 (8) | 12.5†† | |||
| Packs/day | ||||||||||||
| 0.5–1.49 | 99 | 68 (9) | 38.4 | 44 | 65 (8) | 56.8† | 55 | 70 (10) | 23.6 | |||
| 1.5+ | 104 | 65 (9) | 22.1*† | 48 | 62 (8) | 27.1** | 56 | 67 (10) | 17.9† | |||
| Duration (years) | ||||||||||||
| 10–39 | 80 | 59 (8) | 33.8 | 39 | 57 (6) | 38.5 | 41 | 61 (10) | 29.3 | |||
| 40+ | 123 | 71 (10)** | 27.6 | 53 | 69 (6)** | 43.4 | 70 | 73 (7)** | 15.7†† | |||