Table 1

CYP2A6 genotype and smoking habit

GroupGenotypenAgeCCPacks/dayDuration
Values are mean (SD).
CC=lifelong cigarette consumption (pack years); duration=duration of smoking period (years); W=homozygous wild type; D=heterozygote or homozygous mutant for CYP2A6del allele.
*p<0.05 v W.
All smokers (n=203)W14267 ( 9)65 (34)1.61 (0.75)41 (10)
D6165 (10)52 (30)*1.36 (0.63)*39 (11)
Current smokers (n=92)W5464 ( 9)65 (28)1.62 (0.66)41 (10)
D3864 ( 8)53 (26)*1.31 (0.59)*41 ( 9)
Ex-smokers (n=111)W8869 ( 9)65 (37)1.61 (0.80)41 (10)
D2368 (13)51 (35)1.39 (0.71)36 (14)