Group | Genotype | n | Age | CC | Packs/day | Duration |
---|---|---|---|---|---|---|
Values are mean (SD). | ||||||
CC=lifelong cigarette consumption (pack years); duration=duration of smoking period (years); W=homozygous wild type; D=heterozygote or homozygous mutant for CYP2A6del allele. | ||||||
*p<0.05 v W. | ||||||
All smokers (n=203) | W | 142 | 67 ( 9) | 65 (34) | 1.61 (0.75) | 41 (10) |
D | 61 | 65 (10) | 52 (30)* | 1.36 (0.63)* | 39 (11) | |
Current smokers (n=92) | W | 54 | 64 ( 9) | 65 (28) | 1.62 (0.66) | 41 (10) |
D | 38 | 64 ( 8) | 53 (26)* | 1.31 (0.59)* | 41 ( 9) | |
Ex-smokers (n=111) | W | 88 | 69 ( 9) | 65 (37) | 1.61 (0.80) | 41 (10) |
D | 23 | 68 (13) | 51 (35) | 1.39 (0.71) | 36 (14) |