HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS REGISTER		Author Keyword(s) Vol Page [Advanced]

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this link to a friend Similar articles in this journal Similar articles in PubMed Add article to my folders Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Mainie, I Articles by Castell, D O Search for Related Content PubMed PubMed Citation Articles by Mainie, I Articles by Castell, D O

Fundoplication eliminates chronic cough due to non-acid reflux identified by impedance pH monitoring

¹ Division of Gastroenterology and Hepatology, Medical University of South Carolina, Charleston, USA
² Division of Pulmonary, Critical Care and Allergy, Medical University of South Carolina, Charleston, USA
³ Department of Surgery, Medical University of South Carolina, Charleston, USA

Correspondence to:
Correspondence to:
Dr I Mainie
Gastroenterology Fellow, Medical University South Carolina, 96 Jonathan Lucas Street, 210 Clinical Science Building, P O Box 250327 Charleston, SC 29425, USA; mainie{at}musc.edu

The symptoms of extra-oesophageal gastro-oesophageal reflux disease (GORD) (such as chronic cough and hoarseness) are traditionally more difficult to treat than typical GORD symptoms (heartburn and regurgitation). Patients with extra-oesophageal manifestations may require longer and higher doses of acid suppressive therapy. In patients not responding to acid suppressive therapy the physician faces a dilemma as to whether the symptoms are due to ongoing acid reflux, non-acid reflux, or not associated with reflux. We report the case of a 45 year old woman with a history of a chronic cough referred for fundoplication after documenting her symptoms were associated with non-acid reflux using multichannel intraluminal impedance and pH (MII-pH).

Abbreviations: MII-pH, multichannel intraluminal impedance and pH; LES, lower oesophageal sphincter; GOR, gastro-oesophageal reflux; GORD, gastro-oesophageal reflux disease; LNF, laparoscopic Nissen fundoplication

Keywords: cough; non-acid reflux; Nissen fundoplication; multichannel intraluminal impedance

This article has been cited by other articles:

				R. Rosen, J. Fritz, A. Nurko, D. Simon, and S. Nurko Lipid-Laden Macrophage Index Is Not an Indicator of Gastroesophageal Reflux-Related Respiratory Disease in Children Pediatrics, April 1, 2008; 121(4): e879 - e884. [Abstract] [Full Text] [PDF]

				R. Tutuian, I. Mainie, A. Agrawal, D. Adams, and D. O. Castell Nonacid reflux in patients with chronic cough on Acid-suppressive therapy. Chest, August 1, 2006; 130(2): 386 - 391. [Abstract] [Full Text] [PDF]