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Thorax 2005;60:168-170
© 2005 BMJ Publishing Group Ltd & British Thoracic Society


CASE REPORT

Chronic Burkholderia multivorans bronchial infection in a non-cystic fibrosis individual with mannose binding lectin deficiency

J L Whitehouse1, A R Exley1,2, J Foweraker3, D Bilton1

1 Lung Defence Clinic, Papworth Hospital, Cambridge, UK
2 Department of Immunology, Papworth Hospital, Cambridge, UK
3 Health Protection Agency, Clinical Microbiology and Public Health Laboratory, Papworth Hospital, Cambridge, UK

Correspondence to:
Correspondence to:
Dr J L Whitehouse
Lung Defence Clinic, Papworth Hospital, Papworth St Everard, Cambridgeshire CB3 8RE, UK; jo_wh{at}excite.com

The case history is presented of a woman with multiple respiratory infections and mannose binding lectin (MBL) deficiency but no evidence of bronchiectasis who developed a chronic Burkholderia multivorans infection. Careful microbiological assessment is needed in patients with recurrent respiratory infection and the presence of B multivorans should trigger further immunological investigation including assessment of MBL status.


Keywords: Burkholderia multivorans; mannose binding lectin deficiency







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