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Thorax 2005;60:880-881; doi:10.1136/thx.2004.027508
Copyright © 2005 BMJ Publishing Group Ltd & British Thoracic Society

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CASE REPORT

CPAP suppression of awake right-to-left shunting through patent foramen ovale in a patient with obstructive sleep apnoea

C Pinet, J Orehek

Département des Maladies Respiratoires, Hôpital Sainte-Marguerite, Marseille, France

Correspondence to:
Correspondence to:
Dr C Pinet
Département des Maladies Respiratoires, Hôpital Sainte Marguerite, BP 29, 13274 Marseille Cedex 9, France; christophe.pinet{at}mail.ap-hm.fr

The prevalence of an echocardiographically visible patent foramen ovale (PFO) is higher in patients with obstructive sleep apnoea syndrome (OSAS) than in normal controls. We report a patient who presented with OSAS and right-to-left shunting (RLS) through the PFO in whom the RLS disappeared after treatment for 1 week with nocturnal continuous positive airway pressure (CPAP). This case shows the role of OSA in generating an awake RLS through a PFO and its possible reversibility by CPAP. The mechanism of reversible awake RLS through PFO in OSAS is discussed.


Abbreviations: AHI, apnoea/hypopnoea index; CPAP, continuous positive airway pressure; OSAS, obstructive sleep apnoea syndrome; PFO, patent foramen ovale; RLS, right-to-left shunting

Keywords: obstructive sleep apnoea; right-to-left shunting; patent foramen ovale; continuous positive airway pressure







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