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Mycobacterium xenopi infection in an immunosuppressed patient with Crohn’s disease

Department of Pulmonary Diseases, Jeroen Bosch Hospital, ’s Hertogenbosch, The Netherlands

Correspondence to:
Correspondence to:
Dr C J Majoor
Department of Pulmonary Diseases, Jeroen Bosch Hospital, Postbus 90153, ’s Hertogenbosch 5200 ME, The Netherlands; cjmajoor{at}planet.nl

A 48 year old patient with active Crohn’s disease presented with bilateral nodules over his lungs resembling malignant metastasis. Bronchoscopic and pathological examination of the airways and sputum did not show any malignancy. After 6 weeks Mycobacterium xenopi was cultured from his bronchial washings while all other cultures remained negative. Treatment was started with rifampicin, ethambutol, and clarithromycin and, after 9 months of treatment, there was an almost complete resolution of his chest radiograph.

Keywords: Mycobacterium xenopi; immunosuppression; Crohn’s disease