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Multidrug resistant tuberculosis following lung transplantation: treatment with pulmonary resection

¹ Pulmonary Institute, Rabin Medical Center, Beilinson Campus, Petah Tiqva and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
² Department of Cardiothoracic Surgery, Rabin Medical Center, Beilinson Campus, Petah Tiqva and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

Correspondence to:
Correspondence to:
Dr M R Kramer
Pulmonary Institute, Rabin Medical Center, Beilinson Campus, Petah Tiqva 49 100, Israel; kramerm{at}netvision.net.il

ABSTRACT
Recipients of organ transplants are at increased risk for infection owing to their immunosuppressed state and the possibility of contamination of the donor organ. We report a case of multidrug resistant tuberculosis (MDR) transmission via a donor lung. After medical treatment with four drugs had failed, the patient underwent right upper lobectomy. There were no signs of disease on follow up more than 2 years later. To our knowledge, this is the first report of MDR tuberculosis in a lung transplant recipient. The need for a non-conservative approach, including pulmonary resection, to eradicate the infection is emphasised.

Keywords: tuberculosis; lung transplantation; pulmonary resection